The Newquay to London Gatwick route offered by Skybus was underneath a Passenger Service Obligation (PSO) contract collectively funded by the federal government and the council.
Skybus started the service on 23 November with a short-term contract after the earlier operators, Eastern Airways, announced it was on the brink of entering administration.
EasyJet is due to start a brand new twice-weekly service for the route on 23 June.
A spokesperson for Cornwall Airport Newquay stated Ryanair continued to function a year-round service to London Stansted.
Following Skybus’ cancellation of flights they stated: “This decision sits outside of the airport’s control.
“London connectivity does, nevertheless, stay in place.
“Although this is not a direct replacement for the PSO route, London services will operate six days a week across the summer.”
“We are actively working with airline partners and stakeholders to secure sustainable London connectivity for the future,” they added.