Semaglutide guidelines based on BMI may exclude at-risk Indians

Semaglutide guidelines based on BMI may exclude at-risk Indians

Global semaglutide eligibility criteria based on BMI may not reflect Indian risk patterns, potentially excluding high-risk patients who develop cardiovascular disease at lower body weights |Image used for representational purpose only

Global semaglutide eligibility standards based on BMI may not replicate Indian threat patterns, probably excluding high-risk sufferers who develop heart problems at decrease physique weights |Image used for representational function solely
| Photo Credit: AFP

The SELECT trial, led by A. Michael Lincoff and published in The New England Journal of Medicine (2023), confirmed that once-weekly semaglutide lowered main cardiovascular occasions by 20% in adults with a physique mass index (BMI) of 27 or greater and pre-existing heart problems, however with out diabetes. The trial enrolled 17,604 individuals and tracked outcomes over almost 40 months.

But making use of this BMI threshold in India might exclude sufferers in danger, says Aditi Kantipuly, doctor, coaching in preventive drugs and public well being resident at McGill University and visiting scholar on the University of New Mexico.

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