The Washington Nationals battle the Chicago Cubs within the second of their three-game season-opening collection on Saturday. Washington defeated Chicago 10-4 on Thursday afternoon. The Nationals (1-0), who completed fifth within the National League East in 2025 at 66-96, had been 34-47 on the highway final season. The Cubs (0-1), who completed second within the NL Central at 92-70, had been 50-31 on their house area.
First pitch from Wrigley Field in Chicago is about for two:20 p.m. ET. Chicago is a -232 favourite on the cash line (threat $232 to win $100) within the newest Nationals vs. Cubs odds from DraftKings Sportsbook, whereas the full variety of runs Vegas thinks might be scored, or the over/underneath, is 8.5. Before making any Cubs vs. Nationals picks, you should definitely see the Nationals vs. Cubs predictions and betting advice from SportsLine’s proven computer model.
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The SportsLine Projection Model simulates each MLB sport 10,000 occasions. It was a worthwhile 35-29 on top-rated MLB money-line picks final season. It additionally excelled making house run prop picks in 2025, returning practically 30 items of revenue. Anybody following its MLB betting picks at sportsbooks and on betting sites might have seen robust returns.
Now, the model has set its sights on Nationals vs. Cubs and simply locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are a number of MLB odds and betting strains for Cubs vs. Nationals:
Nationals vs. Cubs cash line | Cubs -232, Nationals +190 |
Nationals vs. Cubs over/underneath | 8.5 runs |
Nationals vs. Cubs run line | Cubs -1.5 (-113) |
Nationals vs. Cubs picks | See picks at SportsLine |
Nationals vs. Cubs streaming | Fubo (Try free of charge) |
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Top Nationals vs. Cubs predictions
After 10,000 simulations of Nationals vs. Cubs, the model is going Over 8.5 mixed runs. Chicago had among the best offenses in baseball final 12 months, averaging 4.9 runs per sport. Most of the highest producers are again, together with Pete Crow-Armstrong, Michael Busch, Ian Happ, Nico Hoerner and Seiya Suzuki. The Nationals, in the meantime, ranked twentieth in runs scored final 12 months. They hope construct round gamers akin to James Wood, the crew’s major energy menace, C.J. Abrams, Brady House and Joey Wiemer.
SportsLine’s model initiatives greater than 1.5 whole bases for Wood and Abrams for the Nationals. The Cubs, in the meantime, are projected to recover from 1.5 whole bases from Crow-Armstrong, Alex Bregman and Busch. The model initiatives 9.4 mixed runs scored on common. Get the Nationals vs. Cubs money-line pick at SportsLine.
How to make Cubs vs. Nationals picks
After simulating each pitch of Cubs vs. Nationals 10,000 occasions, the model additionally says one aspect of the cash line has all the worth. You can get that pick at SportsLine.
So who wins Cubs vs. Nationals, and which aspect of the cash line has all the worth? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and discover out.